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Description
ACTH Recombinant Rabbit mAb (SDT-363-92)Product Specification Host Rabbit Synonyms Adrenocorticotropic Hormone, Corticotropin Immunogen Synthetic Peptide Accession P01189 Clone Number SDT 363 92 Antibody Type Recombinant mAb Isotype IgG Application CLIA, Sandwich ELISA Reactivity Hu Cross Reactivity Does not recognize MSH and CLIP Purification Protein A Concentration 2 mg ml Purity >95% by HPLC Conjugation Unconjugated Physical Appearance Liquid Storage Buffer PBS pH7. 4, 0. 03% Proclin 300
Product Specification
| Host | Rabbit |
| Synonyms | Adrenocorticotropic Hormone, Corticotropin |
| Immunogen | Synthetic Peptide |
| Accession | P01189 |
| Clone Number | SDT-363-92 |
| Antibody Type | Recombinant mAb |
| Isotype | IgG |
| Application | CLIA, Sandwich ELISA |
| Reactivity | Hu |
| Cross Reactivity | Does not recognize α-MSH and CLIP |
| Purification | Protein A |
| Concentration | 2 mg/ml |
| Purity | >95% by HPLC |
| Conjugation | Unconjugated |
| Physical Appearance | Liquid |
| Storage Buffer | PBS pH7.4, 0.03% Proclin 300 |
| Stability & Storage | 12 months from date of receipt, 2 to 8 °C as supplied |
Dilution
| application | dilution | species |
| Sandwich ELISA | N/A |
Background
Adrenocorticotropic hormone (ACTH; also adrenocorticotropin, corticotropin) is a polypeptide tropic hormone produced by and secreted by the anterior pituitary gland. It is also used as a medication and diagnostic agent. ACTH is an important component of the hypothalamic-pituitary-adrenal axis and is often produced in response to biological stress (along with its precursor corticotropin-releasing hormone from the hypothalamus). Its principal effects are increased production and release of cortisol and androgens by the cortex and medulla of the adrenal gland, respectively. ACTH is also related to the circadian rhythm in many organisms. Adrenocorticotropin detection can be used in the diagnosis and differential diagnosis of hypopituitary adrenocortical hyperfunction, such as primary aldosteronism, Cushing's syndrome, Cushing's disease, pheochromocytoma, etc.
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